Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.68 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | MME | P08473 | 6/20 | 0.44 |
| ▸ | CAD | P27708 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2793959 | 1.00 | TGFBR1 (0.68) | TGFBR1CA2CA1MMECAD | |
| SCHEMBL2793957 | 1.00 | TGFBR1 (0.68) | TGFBR1CA2CA1MMECAD | |
| SCHEMBL9952519 | 0.82 | TGFBR1 (0.46) | TGFBR1CA2CA1CADNFKB1 | |
| SCHEMBL1147073 | 0.81 | TGFBR1 (0.47) | TGFBR1CADFOLH1RIMKLANAALAD2 | |
| SCHEMBL1147075 | 0.81 | TGFBR1 (0.47) | TGFBR1CADFOLH1RIMKLANAALAD2 | |
| SCHEMBL27637802 | 0.79 | TGFBR1 (0.60) | TGFBR1CA2CA1MMEFOLH1 | |
| SCHEMBL21950137 | 0.79 | TGFBR1 (0.60) | TGFBR1CA2CA1MMEFOLH1 | |
| SCHEMBL14050302 | 0.79 | TGFBR1 (0.60) | TGFBR1CA2CA1MMEFOLH1 | |
| SCHEMBL17987676 | 0.78 | TGFBR1 (0.43) | TGFBR1CA2CA1MMECAD | |
| SCHEMBL5493514 | 0.78 | CA2 (0.52) | TGFBR1CA2CA1MMEFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1376202-A | Stereostructure of decarbamylase and use thereof | KANEGAFUCHI CHEMICAL IND (JP) | 2002-10-23 | — | — | CN | claimed |
| EP-1209234-A1 | STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME | Kaneka Corporation (JP) | 2002-05-29 | — | — | EP | claimed |
| CN-119842679-A | D-threonine aldolase mutant and application thereof | 绵阳晟氏健康科技有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-116287044-A | Application of D-threonine aldolase in preparation of D-serine | 弈柯莱生物科技(上海)股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-1331274-B1 | PROCESS FOR PRODUCING D-SERINE | KYOWA HAKKO BIO CO LTD (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-20110065794-A1 | Wrinkle-preventing and improving composition | SHISEIDO COMPANY, LTD. (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20100168468-A1 | WRINKLE-PREVENTING AND IMPROVING COMPOSITION | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-07-01 | — | — | US | disclosed |
| CN-101227885-A | Wrinkle preventing/improving agent | SHISEIDO CO LTD (JP) | 2008-07-23 | — | — | CN | disclosed |
| EP-1908454-A1 | WRINKLE-PREVENTIVE/AMELIORATING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2008-04-09 | — | — | EP | disclosed |
| EP-1616945-B1 | Process for producing D-N-carbamoyl-alpha-amino acids | KANEGAFUCHI CHEMICAL IND (JP) | 2007-11-21 | — | — | EP | disclosed |
| US-7186532-B2 | Process for producing D-serine | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-03-06 | — | — | US | disclosed |
| EP-0801131-B1 | PROCESS FOR PRODUCING D-N-CARBAMOYL-ALPHA-AMINO ACID | KANEGAFUCHI CHEMICAL IND (JP) | 2007-02-21 | — | — | EP | disclosed |
| EP-1616945-A1 | Process for producing D-N-carbamoyl-alpha-amino acids | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2006-01-18 | — | — | EP | disclosed |
| EP-1616946-A1 | Process for producing D-N-carbamoyl-alpha-amino acids | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-20040072308-A1 | Process for producing d-serine | KYOWA HAKKO BIO CO., LTD. (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1331274-A1 | PROCESS FOR PRODUCING D-SERINE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-07-30 | — | — | EP | disclosed |
| CN-1376202-A | Stereostructure of decarbamylase and use thereof | KANEGAFUCHI CHEMICAL IND (JP) | 2002-10-23 | — | — | CN | disclosed |
| EP-1209234-A1 | STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME | Kaneka Corporation (JP) | 2002-05-29 | — | — | EP | disclosed |
| EP-0801131-A1 | PROCESS FOR PRODUCING D-N-CARBAMOYL-$g(a)-AMINO ACID | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-4237227-A | ENZYMATIC HYDROLYSIS OF A HYDANTOIN | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1980-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168468-A1 | WRINKLE-PREVENTING AND IMPROVING COMPOSITION | COL1A1, COL2A1, COL14A1 | TGFBR1 412/4885CA2 2434/4885CA1 4069/4885 |
| US-20110065794-A1 | Wrinkle-preventing and improving composition | COL1A1, COL2A1, COL14A1 | TGFBR1 412/4885CA2 2434/4885CA1 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.