Quinoline

Quinoline

SCHEMBL27638019

Cc1nccn1C.c1ccc2ncccc2c1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
CYP3A4 P08684 2/20 0.42
KDM4E B2RXH2 2/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
BRD4 O60885 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
PDE10A Q9Y233 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2E1 P05181 1/20 0.38
CYP2A6 P11509 1/20 0.38
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28194485 0.82 ALDH1A1 (0.53) ALDH1A1KDM4ECASP1CASP7HSD17B10
Quinoline SCHEMBL27287160 0.81 ALDH1A1 (0.57) ALDH1A1CYP3A4KDM4ECASP1CASP7
Quinoline SCHEMBL28154035 0.79 ALDH1A1 (0.59) ALDH1A1CYP3A4KDM4ECASP1CASP7
Quinoline SCHEMBL28481300 0.79 ALDH1A1 (0.94) ALDH1A1CYP3A4KDM4ECASP1CASP7
Quinoline SCHEMBL28090681 0.79 ALDH1A1 (0.94) ALDH1A1CYP3A4KDM4ECASP1CASP7
Quinoline SCHEMBL29349478 0.79 ALDH1A1 (0.94) ALDH1A1CYP3A4KDM4ECASP1CASP7
Quinoline SCHEMBL1678429 0.79 ALDH1A1 (0.94) ALDH1A1CYP3A4KDM4ECASP1CASP7
Quinoline SCHEMBL28042102 0.78 ALDH1A1 (0.68) ALDH1A1CYP3A4KDM4ECASP1CASP7
Benzene SCHEMBL18045485 0.77 LPO (0.48) ALDH1A1CYP3A4KDM4EBRD4POLB
Quinoline SCHEMBL29087059 0.77 ALDH1A1 (0.90) ALDH1A1CYP3A4KDM4ECASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100466122-C Electrolytic solution for electrolytic capacitor, and method for producing tetrafluoroaluminate salt of organic onium MITSUBISHI CHEM CORP (JP) 2009-03-04 CN claimed
CN-1708817-A Electrolytic solution for electrolytic capacitor, and method for producing tetrafluoroaluminate salt of organic onium MITSUBISHI CHEM CORP (JP) 2005-12-14 CN claimed
CN-100466122-C Electrolytic solution for electrolytic capacitor, and method for producing tetrafluoroaluminate salt of organic onium MITSUBISHI CHEM CORP (JP) 2009-03-04 CN disclosed
CN-1708817-A Electrolytic solution for electrolytic capacitor, and method for producing tetrafluoroaluminate salt of organic onium MITSUBISHI CHEM CORP (JP) 2005-12-14 CN disclosed