SCHEMBL27638047

SCHEMBL27638047

CCCCOc1ccc(COc2ccc(C(=O)NC(Cc3ccc(OCc4ccccc4)cc3)C(=O)OC)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.74
GAA P10253 1/20 0.74
PPARG P37231 1/20 0.62
ERAP2 Q6P179 2/20 0.59
LNPEP Q9UIQ6 1/20 0.59
TAS1R3 Q7RTX0 1/20 0.56
TAS1R1 Q7RTX1 1/20 0.56
GPR132 Q9UNW8 2/20 0.56
ITGB3 P05106 1/20 0.55
ITGA2B P08514 1/20 0.55
PTPN1 P18031 1/20 0.54
YAP1 P46937 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC2 Q92769 1/20 0.54
NCOR2 Q9Y618 1/20 0.54
LTA4H P09960 1/20 0.54
IL1RN P18510 1/20 0.53
ERAP1 Q9NZ08 1/20 0.53
MEN1 O00255 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122610 1.00 RAB9A (0.74) RAB9AGAAPPARGERAP2LNPEP
SCHEMBL1122821 0.96 RAB9A (0.71) RAB9AGAAPPARGERAP2LNPEP
SCHEMBL1123685 0.94 RAB9A (0.71) RAB9AGAAPPARGERAP2LNPEP
SCHEMBL27638041 0.94 RAB9A (0.71) RAB9AGAAPPARGERAP2LNPEP
SCHEMBL1123687 0.94 RAB9A (0.71) RAB9AGAAPPARGERAP2LNPEP
SCHEMBL1122923 0.94 RAB9A (0.71) RAB9AGAAPPARGERAP2LNPEP
SCHEMBL1123055 0.93 GAA (0.80) RAB9AGAAPPARGERAP2LNPEP
SCHEMBL1122645 0.93 GAA (0.69) RAB9AGAAPPARGERAP2LNPEP
SCHEMBL27658965 0.93 GAA (0.69) RAB9AGAAPPARGERAP2LNPEP
SCHEMBL1123147 0.92 GAA (0.71) RAB9AGAAPPARGERAP2LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1835914-A New benzamides as PPAR[upsilon] modulators S A L V A T LAB SA (ES) 2006-09-20 CN claimed
CN-1835914-A New benzamides as PPAR[upsilon] modulators S A L V A T LAB SA (ES) 2006-09-20 CN disclosed