SCHEMBL27658965

SCHEMBL27658965

COC(=O)C(Cc1ccc(OCc2ccccc2)cc1)NC(=O)c1ccc(OCCCc2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.69
RAB9A P51151 1/20 0.69
PPARG P37231 1/20 0.61
ERAP2 Q6P179 3/20 0.58
LNPEP Q9UIQ6 2/20 0.58
GPR132 Q9UNW8 2/20 0.55
ITGB3 P05106 1/20 0.54
ITGA2B P08514 1/20 0.54
YAP1 P46937 5/20 0.54
PTPN1 P18031 1/20 0.53
LTA4H P09960 1/20 0.53
IL1RN P18510 1/20 0.52
ERAP1 Q9NZ08 1/20 0.52
ALDH1A1 P00352 2/20 0.52
LMNA P02545 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
GLA P06280 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122645 1.00 GAA (0.69) GAARAB9APPARGERAP2LNPEP
SCHEMBL1123147 0.95 GAA (0.71) GAARAB9APPARGERAP2LNPEP
SCHEMBL1122923 0.93 RAB9A (0.71) GAARAB9APPARGERAP2LNPEP
SCHEMBL1123685 0.93 RAB9A (0.71) GAARAB9APPARGERAP2LNPEP
SCHEMBL1123687 0.93 RAB9A (0.71) GAARAB9APPARGERAP2LNPEP
SCHEMBL27638041 0.93 RAB9A (0.71) GAARAB9APPARGERAP2LNPEP
SCHEMBL1122610 0.93 RAB9A (0.74) GAARAB9APPARGERAP2LNPEP
SCHEMBL27638047 0.93 RAB9A (0.74) GAARAB9APPARGERAP2LNPEP
SCHEMBL1123055 0.92 GAA (0.80) GAARAB9APPARGERAP2LNPEP
SCHEMBL1122745 0.91 GPR132 (0.66) GAARAB9APPARGERAP2LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1835914-A New benzamides as PPAR[upsilon] modulators S A L V A T LAB SA (ES) 2006-09-20 CN disclosed