Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetaldehyde SCHEMBL8007442 | 0.85 | CTSK (0.44) | CTSKTSHRCA1CA7CA12 | |
| SCHEMBL303868 | 0.84 | — | — | |
| Formamide SCHEMBL28296149 | 0.83 | CTSK (0.40) | CTSKTSHRCA1CA7CA12 | |
| SCHEMBL28175005 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL27497408 | 0.82 | DGAT1 (0.42) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL30402270 | 0.82 | DGAT1 (0.42) | CA1CA7CA12CA14TDP1 | |
| Acetic Acid SCHEMBL3543052 | 0.78 | MEN1 (0.41) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL15512903 | 0.78 | TDP1 (0.39) | CTSKCA1CA7CA12CA14 | |
| Propane SCHEMBL28996705 | 0.78 | CA1 (0.44) | CTSKCA1CA7CA12CA14 | |
| Alcohol SCHEMBL23629777 | 0.76 | TDP1 (0.47) | CTSKCA1CA7CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1713908-B | Aminoalkoxyindoles as 5-HT6-receptor ligands for the treatment of CNA-disorders | HOFFMANN LA ROCHE | 2010-05-12 | — | — | CN | disclosed |
| CN-1713908-A | Aminoalkoxyindoles as 5-HT6-receptor ligands for the treatment of CNA-disorders | HOFFMANN LA ROCHE (CH) | 2005-12-28 | — | — | CN | disclosed |