Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.65 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 2/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165065 | 1.00 | TRPV1 (0.65) | TRPV1P4HA1P4HTMLDHATRPM8 | |
| SCHEMBL27638998 | 0.84 | TRPV1 (0.63) | TRPV1TGFBR1L3MBTL1 | |
| SCHEMBL3881337 | 0.81 | TRPV1 (0.65) | TRPV1RORC | |
| SCHEMBL8303037 | 0.79 | LDHA (0.57) | TRPV1P4HA1P4HTMLDHAL3MBTL1 | |
| SCHEMBL4926077 | 0.79 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL6226027 | 0.76 | KDM4E (0.50) | TRPV1P4HTMRORC | |
| SCHEMBL4808010 | 0.75 | RORC (0.59) | TRPV1RORC | |
| Hydrochloric Acid SCHEMBL6220633 | 0.75 | KDM4E (0.49) | TRPV1P4HTMRORC | |
| SCHEMBL14252860 | 0.75 | TRPV1 (0.76) | TRPV1 | |
| SCHEMBL14263130 | 0.75 | TRPV1 (0.76) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1820008-A | Substituted quinolin-4-ylamine analogues | NEUROGEN CORP (US) | 2006-08-16 | — | — | CN | disclosed |