Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620578 | 0.86 | MTNR1A (0.42) | MTNR1AMTNR1BGAAMCL1KDM4E | |
| SCHEMBL27620013 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BGAAMCL1KDM4E | |
| SCHEMBL4473320 | 0.81 | TNF (0.53) | MTNR1AMTNR1BGAAMCL1KDM4E | |
| SCHEMBL27619992 | 0.80 | MCL1 (0.55) | MCL1BCL2 | |
| SCHEMBL21051475 | 0.80 | GLO1 (0.50) | MTNR1AMTNR1BGAAMCL1KDM4E | |
| SCHEMBL4466329 | 0.79 | TNF (0.60) | GAAMCL1KDM4E | |
| SCHEMBL4459699 | 0.78 | TNF (0.56) | MTNR1AMTNR1BGAAMCL1KDM4E | |
| SCHEMBL30396580 | 0.78 | F2 (0.45) | GAAKDM4E | |
| SCHEMBL6384442 | 0.78 | MTNR1A (0.48) | MTNR1AMTNR1BHDAC3HDAC1HDAC2 | |
| SCHEMBL3689068 | 0.78 | F2 (0.45) | GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1751037-A | Sulfonamide derivatives as PPAR modulators | LILLY CO ELI (US) | 2006-03-22 | — | — | CN | disclosed |