Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 12/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509614 | 0.83 | CNR1 (0.68) | GABRA2GABRB2 | |
| SCHEMBL24208917 | 0.81 | GABRA2 (0.55) | GABRA2GABRB2OPRL1 | |
| SCHEMBL24208909 | 0.74 | GABRA2 (0.52) | GABRA2GABRB2 | |
| SCHEMBL4501027 | 0.73 | GABRA2 (0.65) | GABRA2GABRB2OPRL1 | |
| SCHEMBL4510979 | 0.72 | GABRA2 (1.00) | GABRA2GABRB2 | |
| SCHEMBL14621770 | 0.70 | CNR1 (0.61) | DPP4DPP8ALDH1A1 | |
| SCHEMBL14329888 | 0.70 | ALDH1A1 (0.94) | ALDH1A1 | |
| SCHEMBL8259356 | 0.69 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL6701268 | 0.69 | CNR1 (0.72) | — | |
| SCHEMBL4020434 | 0.69 | CNR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1865248-A | Imidazole-4-carboxamide derivatives, preparation and use thereof for treatment of obesity | BAYER PHARMACEUTICALS CORP (US) | 2006-11-22 | — | — | CN | disclosed |