Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27639471 | 0.87 | CNR1 (0.43) | CNR2CNR1ALDH1A1DHFRCYP1A2 | |
| SCHEMBL27836801 | 0.84 | CNR2 (0.45) | CNR2CNR1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27742966 | 0.82 | CNR1 (0.61) | CNR2CNR1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL27620325 | 0.82 | CNR1 (0.39) | CNR2CNR1ALDH1A1DHFRCYP1A2 | |
| SCHEMBL4054662 | 0.82 | CNR1 (0.45) | CNR2CNR1ALDH1A1DHFRCYP1A2 | |
| SCHEMBL27854790 | 0.82 | HTT (0.47) | CNR2CNR1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL27938671 | 0.81 | CNR1 (0.44) | CNR2CNR1ALDH1A1MAPK1TLR7 | |
| SCHEMBL27742975 | 0.80 | CNR1 (0.43) | CNR2CNR1ALDH1A1DHFRCYP1A2 | |
| SCHEMBL27795718 | 0.79 | CNR1 (0.44) | CNR2CNR1CYP1A2CYP2C19TLR7 | |
| SCHEMBL27854817 | 0.79 | CTSK (0.47) | CNR2CNR1DHFRCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1756747-A | Anti-inflammatory agents | DECIPHERA PHARMACEUTICALS LLC (US) | 2006-04-05 | — | — | CN | disclosed |