SCHEMBL27640499

SCHEMBL27640499

COc1ccc(/C=C(\C(=O)O)c2ccccc2)cc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
ALDH1A1 P00352 3/20 0.62
TUBB1 Q9H4B7 7/20 0.61
TUBB4A P04350 4/20 0.61
TUBB P07437 4/20 0.61
TUBA3C P0DPH7 4/20 0.61
TUBA1B P68363 4/20 0.61
TUBA4A P68366 4/20 0.61
TUBB4B P68371 4/20 0.61
TUBB3 Q13509 4/20 0.61
TUBB2A Q13885 4/20 0.61
TUBB8 Q3ZCM7 4/20 0.61
TUBA3E Q6PEY2 4/20 0.61
TUBA1A Q71U36 4/20 0.61
TUBA1C Q9BQE3 4/20 0.61
TUBB6 Q9BUF5 4/20 0.61
TUBB2B Q9BVA1 4/20 0.61
AKR1C3 P42330 3/20 0.61
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2523113 0.89 MEN1 (0.62) MEN1KMT2AALDH1A1AKR1C3POLB
SCHEMBL2951322 0.89 MEN1 (0.62) MEN1KMT2AALDH1A1AKR1C3POLB
SCHEMBL2951324 0.89 MEN1 (0.62) MEN1KMT2AALDH1A1AKR1C3POLB
SCHEMBL5700860 0.86 TUBB1 (0.72) MEN1KMT2ATUBB1TUBB4ATUBB
SCHEMBL15675107 0.86 TUBB1 (0.72) MEN1KMT2ATUBB1TUBB4ATUBB
SCHEMBL27772857 0.86 ALOX5 (0.57) MEN1KMT2AALDH1A1TUBB1TUBB4A
SCHEMBL2529255 0.84 KMT2A (0.60) MEN1KMT2AALDH1A1TUBB1TUBB4A
SCHEMBL2523087 0.82 AKR1C3 (0.64) MEN1KMT2AALDH1A1AKR1C3POLB
SCHEMBL2954274 0.82 AKR1C3 (0.64) MEN1KMT2AALDH1A1AKR1C3POLB
SCHEMBL2526753 0.82 AKR1C3 (0.64) MEN1KMT2AALDH1A1AKR1C3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1723884-A Cis-1, the diphenyl ethylene derivatives that 2-replaces are used to prepare the purposes of the medicine of treatment or prevent diabetes INST OF RADIO MEDICINE MILITAR (CN) 2006-01-25 CN disclosed