Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147675 | 0.84 | TLR8 (0.45) | TLR8PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5885519 | 0.78 | TLR8 (0.37) | TLR8PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5885008 | 0.78 | S1PR1 (0.37) | TLR8PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12856555 | 0.78 | MAPT (0.40) | TLR8PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2766658 | 0.78 | TLR8 (0.43) | TLR8PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4415267 | 0.76 | EGFR (0.34) | TLR8ALDH1A1MCHR1HSD17B10SMN1; SMN2 | |
| SCHEMBL13957126 | 0.75 | PTPN11 (0.50) | S1PR1S1PR3SMN1; SMN2MAPTHPGD | |
| SCHEMBL11957246 | 0.73 | TLR8 (0.33) | TLR8PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL132074 | 0.73 | TLR8 (0.37) | TLR8PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5885877 | 0.73 | HTT (0.39) | ALDH1A1GAADHODHHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723455-B2 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| EP-1656408-B1 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | MERCK PATENT GMBH (DE) | 2010-04-14 | — | — | EP | disclosed |
| US-7288617-B2 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2007-10-30 | — | — | US | disclosed |
| US-20070060736-A1 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2007-03-15 | — | — | US | disclosed |
| EP-1656408-A2 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005014689-A2 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2005-02-17 | — | — | WO | disclosed |
| EP-1381639-B1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-09-08 | — | — | EP | disclosed |
| US-20040135131-A1 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2004-07-15 | — | — | US | disclosed |
| EP-1381639-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002077060-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2002-10-03 | — | — | WO | disclosed |