Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2764055 | 0.84 | TLR8 (0.38) | TLR8ALDH1A1GAAPDE4APDE4B | |
| SCHEMBL13607200 | 0.83 | KDM4E (0.47) | TLR8ALDH1A1GAAPDE4APDE4B | |
| SCHEMBL5885519 | 0.83 | TLR8 (0.37) | TLR8ALDH1A1GAAPDE4APDE4B | |
| SCHEMBL5885008 | 0.83 | S1PR1 (0.37) | TLR8ALDH1A1GAAPDE4APDE4B | |
| SCHEMBL2766658 | 0.81 | TLR8 (0.43) | TLR8ALDH1A1GAAPDE4APDE4B | |
| SCHEMBL13044262 | 0.81 | TLR8 (0.36) | TLR8ALDH1A1GAAPDE4APDE4B | |
| SCHEMBL801374 | 0.81 | TLR8 (0.36) | TLR8ALDH1A1GAAPDE4APDE4B | |
| SCHEMBL12856555 | 0.80 | MAPT (0.40) | TLR8ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL5649980 | 0.79 | TLR8 (0.54) | TLR8ALDH1A1MCHR1KDM4EL3MBTL1 | |
| SCHEMBL5885877 | 0.78 | HTT (0.39) | ALDH1A1GAAMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288617-B2 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2007-10-30 | — | — | US | disclosed |
| EP-1381639-B1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-09-08 | — | — | EP | disclosed |
| US-20040135131-A1 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2004-07-15 | — | — | US | disclosed |
| EP-1381639-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002077060-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2002-10-03 | — | — | WO | disclosed |