Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414160 | 0.81 | MCHR1 (0.36) | EGFRNR1I2TLR8ALDH1A1NPC1 | |
| SCHEMBL2764055 | 0.76 | TLR8 (0.38) | TLR8ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4415268 | 0.72 | THRB (0.30) | — | |
| SCHEMBL1823358 | 0.69 | KIF11 (0.42) | EGFRALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL14620935 | 0.68 | — | — | |
| SCHEMBL15195768 | 0.68 | FFAR1 (0.48) | ALDH1A1NPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL31026091 | 0.67 | PTAFR (0.39) | ALDH1A1NPC1RAB9AL3MBTL1HTT | |
| SCHEMBL12167685 | 0.66 | HTR1A (0.38) | NR1I2TLR8 | |
| SCHEMBL12303998 | 0.66 | MRGPRX4 (0.44) | TLR8ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5147675 | 0.66 | TLR8 (0.45) | TLR8ALDH1A1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638594-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2009-12-29 | — | — | US | disclosed |
| US-7323533-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2008-01-29 | — | — | US | disclosed |
| US-20070265473-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2007-11-15 | — | — | US | disclosed |
| EP-1427768-B1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | MERCK PATENT GMBH (DE) | 2007-01-24 | — | — | EP | disclosed |
| US-20050038223-A1 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| EP-1427768-A2 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003020790-A2 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2003-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265473-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | ALDH1A2, SELE, PPOX | EGFR 2814/4885NR1I2 524/4885TLR8 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.