Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29846523 | 0.85 | CTSK (0.33) | CTSKCA1CA2CA7 | |
| SCHEMBL27921297 | 0.81 | MEN1 (0.33) | CTSKCA1CA2CA7 | |
| SCHEMBL27845696 | 0.81 | MEN1 (0.33) | CTSKCA1CA2CA7 | |
| SCHEMBL27710328 | 0.81 | MEN1 (0.33) | CTSKCA1CA2CA7 | |
| SCHEMBL27951667 | 0.79 | CTSK (0.31) | CTSKCA1CA2CA7 | |
| SCHEMBL25698306 | 0.75 | NPC1 (0.36) | CTSKHDAC6CA1CA7 | |
| SCHEMBL27768752 | 0.73 | MEN1 (0.36) | CTSK | |
| SCHEMBL27737548 | 0.73 | — | — | |
| SCHEMBL24046046 | 0.71 | CTSK (0.32) | NOS1NOS3NOS2CTSKCA1 | |
| SCHEMBL14897959 | 0.71 | CA1 (0.32) | CTSKCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1856498-A | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LAB (US) | 2006-11-01 | — | — | CN | disclosed |