Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.48 |
| ▸ | PRKACA | P17612 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
| ▸ | GRK5 | P34947 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078942 | 0.90 | TOP1 (0.47) | LRRK2PRKACAIKBKBCHUKDAPK3 | |
| Benzene SCHEMBL28095234 | 0.83 | IKBKB (0.53) | LRRK2PRKACAIKBKBCHUKDAPK3 | |
| SCHEMBL28868 | 0.83 | IKBKB (0.53) | LRRK2PRKACAIKBKBCHUKDAPK3 | |
| SCHEMBL28859500 | 0.83 | IKBKB (0.53) | LRRK2PRKACAIKBKBCHUKDAPK3 | |
| Hydrochloric Acid SCHEMBL8685286 | 0.81 | IKBKB (0.52) | LRRK2PRKACAIKBKBCHUKDAPK3 | |
| Hydrochloric Acid SCHEMBL1238416 | 0.81 | IKBKB (0.52) | LRRK2PRKACAIKBKBCHUKDAPK3 | |
| Hydrochloric Acid SCHEMBL5385347 | 0.81 | IKBKB (0.52) | LRRK2PRKACAIKBKBCHUKDAPK3 | |
| Hydrochloric Acid SCHEMBL21643628 | 0.81 | IKBKB (0.52) | LRRK2PRKACAIKBKBCHUKDAPK3 | |
| Hydrochloric Acid SCHEMBL17396321 | 0.81 | IKBKB (0.52) | LRRK2PRKACAIKBKBCHUKDAPK3 | |
| SCHEMBL2879644 | 0.81 | IKBKB (0.52) | LRRK2PRKACAIKBKBCHUKDAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083845-A | A kind of 1,5 naphthyridine type luminous organic material compounds and synthetic method thereof and application | 金陵科技学院 | 2016-11-09 | — | — | CN | claimed |
| CN-106083845-A | A kind of 1,5 naphthyridine type luminous organic material compounds and synthetic method thereof and application | 金陵科技学院 | 2016-11-09 | — | — | CN | disclosed |
| CN-1720238-B | Neurologically-active compounds | PRANA BIOTECHNOLOGY LTD | 2011-08-03 | — | — | CN | disclosed |
| CN-1720238-A | Neurologically-active compounds | PRANA BIOTECHNOLOGY LTD (AU) | 2006-01-11 | — | — | CN | disclosed |