Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18131148 | 0.78 | GRM5 (0.46) | CASP1JAK2KDM4EALDH1A1HPGD | |
| SCHEMBL27909833 | 0.77 | KDM4E (0.46) | CASP1JAK2KDM4EALDH1A1HPGD | |
| SCHEMBL7360342 | 0.76 | BCAT2 (0.51) | KDM4EPARP1ALOX5APFEN1 | |
| SCHEMBL17894102 | 0.75 | KMT2A (0.54) | CASP1ALDH1A1KMT2APARP1ALOX5AP | |
| SCHEMBL30810258 | 0.75 | KMT2A (0.54) | CASP1ALDH1A1KMT2APARP1ALOX5AP | |
| SCHEMBL1206950 | 0.73 | FLT1 (0.44) | CASP1KDM1AJAK2ALDH1A1HPGD | |
| SCHEMBL17111537 | 0.73 | JAK2 (0.46) | CASP1JAK2KDM4EALDH1A1HPGD | |
| SCHEMBL29543460 | 0.73 | JAK2 (0.43) | CASP1JAK2KDM4EALDH1A1HPGD | |
| SCHEMBL28172285 | 0.73 | CNR2 (0.47) | CASP1JAK2KDM4EALDH1A1HPGD | |
| SCHEMBL17111766 | 0.72 | NTRK1 (0.44) | CASP1JAK2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100475777-C | Amide type carboxamide derivative | TANABE SEIYAKU CO (JP) | 2009-04-08 | — | — | CN | disclosed |
| CN-1860097-A | Amide-type carboxamide derivative | TANABE SEIYAKU CO (JP) | 2006-11-08 | — | — | CN | disclosed |