Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909833 | 0.85 | KDM4E (0.46) | CSNK1A1DYRK1BPARP1DHODHRAB9A | |
| SCHEMBL15903099 | 0.81 | DHODH (0.44) | BCAT2PARP1DHODHRAB9AGRM5 | |
| SCHEMBL1967459 | 0.81 | BCAT2 (0.51) | BCAT2CSNK1A1TYRO3DYRK1BALOX5AP | |
| SCHEMBL3529606 | 0.81 | BCAT2 (0.51) | BCAT2CSNK1A1TYRO3DYRK1BALOX5AP | |
| SCHEMBL27684371 | 0.81 | BCAT2 (0.51) | BCAT2CSNK1A1TYRO3DYRK1BALOX5AP | |
| SCHEMBL4675603 | 0.78 | RAB9A (0.40) | DHODHRAB9ASMN1; SMN2 | |
| SCHEMBL197002 | 0.78 | BCAT2 (0.71) | BCAT2PARP1MAPTTDP1KDM4E | |
| SCHEMBL25093211 | 0.77 | BCAT2 (0.47) | BCAT2CSNK1A1TYRO3DYRK1BALOX5AP | |
| SCHEMBL30810258 | 0.77 | KMT2A (0.54) | BCAT2CSNK1A1TYRO3DYRK1BALOX5AP | |
| SCHEMBL17894102 | 0.77 | KMT2A (0.54) | BCAT2CSNK1A1TYRO3DYRK1BALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061440-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2023-04-20 | — | — | WO | disclosed |
| EP-4157888-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2023-04-05 | — | — | EP | disclosed |
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |
| CN-105254623-A | SUBSTITUTED BENZAMIDES | HOFFMANN LA ROCHE | 2016-01-20 | — | — | CN | disclosed |
| CN-102686563-A | Substituted benzamide derivatives | HOFFMANN LA ROCHE | 2012-09-19 | — | — | CN | disclosed |
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |