Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 12/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 12/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 12/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977059 | 0.81 | PTGIR (0.84) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL27662722 | 0.79 | PTGIR (0.58) | PTGIRADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL27662821 | 0.79 | PTGIR (0.60) | PTGIRADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL5807468 | 0.77 | PTGIR (1.00) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL5827927 | 0.76 | PTGIR (0.61) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL28942366 | 0.74 | PTGIR (0.64) | PTGIRADRA2AADRA2BADRA2C | |
| Acetic Acid SCHEMBL6967870 | 0.74 | PTGIR (0.73) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL27662630 | 0.72 | ADRA2A (0.61) | PTGIRADRA2AADRA2BADRA2C | |
| SCHEMBL27642225 | 0.72 | ADRA2A (0.52) | PTGIRADRA2AADRA2BADRA2C | |
| SCHEMBL27642292 | 0.70 | ADRA2A (0.47) | PTGIRADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1849308-A | Thiophenylaminoimidazolines | ROCHE PALO ALTO LLC (CH) | 2006-10-18 | — | — | CN | claimed |
| CN-1849308-A | Thiophenylaminoimidazolines | ROCHE PALO ALTO LLC (CH) | 2006-10-18 | — | — | CN | disclosed |