Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.84 |
| ▸ | ADRA2A | P08913 | 14/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 14/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 14/20 | 0.67 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | HTR1B | P28222 | 1/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807468 | 0.92 | PTGIR (1.00) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| Acetic Acid SCHEMBL6967870 | 0.92 | PTGIR (0.73) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL5827927 | 0.82 | PTGIR (0.61) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL27642201 | 0.81 | PTGIR (0.62) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL5827504 | 0.77 | HTR1D (0.66) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL24891637 | 0.76 | PTGIR (0.53) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL27642200 | 0.76 | PTGIR (0.56) | PTGIRADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL13985246 | 0.75 | ADRA2A (0.79) | PTGIRADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL13024513 | 0.75 | ADRA2A (0.79) | PTGIRADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL4779741 | 0.75 | ADRA2A (0.79) | PTGIRADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944603-B1 | PROCESS FOR MAKING 2-AMINO-2-IMIDAZOLINE, GUANIDINE, AND 2-AMINO-3,4,5,6-TETRAHYDROPYRIMIDINE DERIVATIVES | PROCTER & GAMBLE (US) | 2003-02-19 | — | — | EP | disclosed |
| US-6066740-A | Process for making 2-amino-2-imidazoline, guanidine and 2-amino-3,4,5,6-tetrahydropyrimidine derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2000-05-23 | — | — | US | disclosed |
| EP-0944603-A1 | PROCESS FOR MAKING 2-AMINO-2-IMIDAZOLINE, GUANIDINE, AND 2-AMINO-3,4,5,6-TETRAHYDROPYRIMIDINE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023595-A1 | PROCESS FOR MAKING 2-AMINO-2-IMIDAZOLINE, GUANIDINE, AND 2-AMINO-3,4,5,6-TETRAHYDROPYRIMIDINE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |