⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL27467126 | 0.95 | FAAH (0.52) | — | |
| SCHEMBL27976 | 0.82 | MGAM (0.61) | — | |
| SCHEMBL28455549 | 0.80 | FAAH (0.47) | — | |
| SCHEMBL12305774 | 0.79 | — | — | |
| SCHEMBL12305750 | 0.79 | — | — | |
| SCHEMBL15688315 | 0.79 | MGAM (0.58) | — | |
| SCHEMBL1331006 | 0.79 | — | — | |
| SCHEMBL26568 | 0.79 | — | — | |
| SCHEMBL27515496 | 0.79 | TSHR (0.50) | — | |
| SCHEMBL1160631 | 0.79 | TSHR (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115772137-A | Preparation method of febuxostat | 济宁晟泰药业有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-109053479-B | Method for synthesizing quaternary amine inner salt | 兆科药业（合肥）有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-102627596-B | A kind of preparation method of Esomeprazole | TIANJIN JINGYIN PHARMACEUTICAL BIOTECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2016-01-27 | — | — | CN | claimed |
| CN-102627596-A | Preparation method of 4-hydroxy-2-oxo-1-pyrrolidine acetamide | TIANJIN JINGYIN PHARMACEUTICAL BIOTECHNOLOGY DEV CO LTD | 2012-08-08 | — | — | CN | claimed |
| US-20040248250-A1 | Method for modifying enzyme and oxidoreductive variant | KANEKA CORPORATION (JP) | 2004-12-09 | — | — | US | claimed |
| EP-0967271-B1 | NOVEL CARBONYL REDUCTASE, GENE THAT ENCODES THE SAME, AND METHOD OF UTILIZING THESE | KANEKA CORP (JP) | 2004-10-20 | — | — | EP | claimed |
| EP-1416050-A1 | METHOD OF MODIFYING ENZYME AND OXIDOREDUCTASE VARIANT | KANEKA CORPORATION (JP) | 2004-05-06 | — | — | EP | claimed |
| US-6448052-B2 | TO CONVERT ETHYL 4-CHLOROACETOACETATE USING NADPH AS A COENZYME TO PRODUCE ETHYL (S)-4-CHLORO-3-HYDROXYBUTYRATE; SUBSTRATE SPECIFICITY, NO ACTIVITY TO ETHYL ACETOACETATE, SPECIFIED OPTIMAL PH AND TEMPERATURE; ENZYME FROM CANDIDA | KANEKA CORPORATION (JP) | 2002-09-10 | — | — | US | claimed |
| US-20020006651-A1 | Carbonyl reductase enzyme and methods for its use | KANEKA CORPORATION | 2002-01-17 | — | — | US | claimed |
| EP-0967271-A1 | NOVEL CARBONYL REDUCTASE, GENE THAT ENCODES THE SAME, AND METHOD OF UTILIZING THESE | KANEKA CORPORATION (JP) | 1999-12-29 | — | — | EP | claimed |
| US-12577373-B2 | Carbodiimide composition, curing agent composition, coating composition and resin cured product | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2026-03-17 | — | — | US | disclosed |
| US-20230135772-A1 | CARBODIIMIDE COMPOSITION, CURING AGENT COMPOSITION, COATING COMPOSITION AND RESIN CURED PRODUCT | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-05-04 | — | — | US | disclosed |
| CN-115772137-A | Preparation method of febuxostat | 济宁晟泰药业有限公司 | 2023-03-10 | — | — | CN | disclosed |
| EP-4130154-A1 | CARBODIIMIDE COMPOSITION, HARDENER COMPOSITION, COATING COMPOSITION, AND CURED RESIN OBJECT | Asahi Kasei Kabushiki Kaisha (JP) | 2023-02-08 | — | — | EP | disclosed |
| CN-115190901-A | Carbodiimide composition, curing agent composition, coating composition, and resin cured product | 旭化成株式会社 | 2022-10-14 | — | — | CN | disclosed |
| US-4008246-A | Aminothiazole derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-02-15 | — | — | US | disclosed |
| US-4001425-A | METHODS OF TREATING HYPERTENSION AND PHARMACEUTICAL COMPOSITIONS COMPRISING 1-TERTIARY-ALKYL-3-(SUBSTITUTED FURYL)UREAS AS ANTIHYPERTENSIVE AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3969370-A | 1-Tertiary-alkyl-3-(substituted furyl)ureas as antihypertensive agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3965168-A | CITRIC ACID INTERMEDIATE | ETHYL CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |
| US-3960941-A | CHEMICAL INTERMEDIATE FOR CITRIC ACID | ETHYL CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |