Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 8/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 8/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665779 | 0.88 | SLC1A2 (0.39) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 | |
| SCHEMBL27644337 | 0.85 | SLC7A5 (0.41) | SLC1A3SLC1A2SLC1A1SLC7A5ALDH1A1 | |
| SCHEMBL27644197 | 0.85 | SLC1A2 (0.41) | SLC1A3SLC1A2SLC1A1SLC7A5ALDH1A1 | |
| SCHEMBL27665292 | 0.84 | ALDH1A1 (0.40) | SLC1A3SLC1A2SLC1A1SLC7A5ALDH1A1 | |
| SCHEMBL27643954 | 0.84 | GRIK1 (0.39) | SLC1A3SLC1A2SLC1A1SLC7A5ALDH1A1 | |
| SCHEMBL27665306 | 0.82 | SLC1A2 (0.41) | SLC1A3SLC1A2SLC1A1SLC7A5ALDH1A1 | |
| SCHEMBL27643941 | 0.82 | SLC1A2 (0.41) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 | |
| SCHEMBL27644008 | 0.81 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 | |
| SCHEMBL27665667 | 0.80 | SLC1A2 (0.42) | SLC1A3SLC1A2SLC1A1SLC7A5HTT | |
| SCHEMBL27665798 | 0.80 | SLC1A2 (0.39) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |