Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KYNU | Q16719 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644271 | 0.85 | SLC1A3 (0.38) | SLC7A5SLC1A3SLC1A2SLC1A1GRM1 | |
| SCHEMBL27644122 | 0.85 | TAS1R3 (0.37) | SLC7A5KDM4EALDH1A1HTT | |
| SCHEMBL27644708 | 0.83 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1KDM4E | |
| SCHEMBL4986115 | 0.83 | KDM4E (0.34) | GRM1KDM4EALDH1A1HTT | |
| SCHEMBL27644802 | 0.82 | GRM1 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1GRM1 | |
| SCHEMBL27665304 | 0.82 | ALDH1A1 (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL27644384 | 0.79 | SLC7A5 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1KDM4E | |
| SCHEMBL27665306 | 0.79 | SLC1A2 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL27665588 | 0.78 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL27644498 | 0.78 | SLC7A5 (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |