Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644704 | 0.90 | GRM2 (0.48) | HTR2AHTR2BHTR2CEPHX1MAPT | |
| SCHEMBL27665175 | 0.89 | HTR2A (0.52) | HTR2AHTR2BHTR2CEPHX1ADRA2C | |
| SCHEMBL27644132 | 0.86 | HTR2A (0.55) | HTR2AHTR2BHTR2CEPHX1ADRA2C | |
| SCHEMBL27644256 | 0.85 | PPARA (0.44) | ADRA1AMAPTCYP1A2USP2CYP3A4 | |
| SCHEMBL27644420 | 0.84 | SMN1; SMN2 (0.40) | EPHX1ADRA1AMAPTCYP1A2USP2 | |
| SCHEMBL27644217 | 0.83 | PNMT (0.44) | GRM2GRM3PPARAPPARG | |
| SCHEMBL27643899 | 0.81 | GRM2 (0.47) | HTR2AHTR2BHTR2CEPHX1MAPT | |
| SCHEMBL27644799 | 0.80 | GRM2 (0.50) | HTR2AHTR2BHTR2CEPHX1MAPT | |
| SCHEMBL31370333 | 0.80 | GRM2 (0.60) | HTR2AHTR2BHTR2CEPHX1MAPT | |
| SCHEMBL27643905 | 0.80 | EPHX1 (0.45) | HTR2AHTR2BHTR2CEPHX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |