Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644166 | 0.89 | HRH3 (0.40) | PPARAPPARGEPHX2HRH3BLM | |
| SCHEMBL27644563 | 0.88 | PPARA (0.46) | PPARAPPARGEPHX2GRB2HRH3 | |
| SCHEMBL27644381 | 0.85 | HTR2A (0.49) | PPARAPPARGDPP4MEN1USP2 | |
| SCHEMBL27644420 | 0.85 | SMN1; SMN2 (0.40) | BLMACEKDM4EMEN1USP2 | |
| SCHEMBL27665810 | 0.84 | GRB2 (0.43) | PPARAPPARGEPHX2GRB2BLM | |
| SCHEMBL27644318 | 0.80 | MMP2 (0.41) | PPARAPPARGEPHX2HRH3BLM | |
| SCHEMBL27644752 | 0.79 | GRM8 (0.41) | PPARAHRH3SLC6A9DPP4 | |
| SCHEMBL27644051 | 0.78 | TAAR1 (0.41) | PPARAPPARGBLMPPARDMEN1 | |
| SCHEMBL27665386 | 0.78 | PPARA (0.42) | PPARAPPARGEPHX2HRH3BLM | |
| SCHEMBL4993849 | 0.77 | PPARA (0.55) | PPARAPPARGEPHX2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |