Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | WHR1 | P49842 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095445 | 0.78 | SSTR2 (0.39) | DRD2DRD3TLR7PAK1TRPV1 | |
| SCHEMBL27644956 | 0.72 | NPC1 (0.50) | SCD | |
| SCHEMBL5543629 | 0.68 | ME3 (0.41) | CNR1CNR2PHGDH | |
| SCHEMBL5543622 | 0.68 | HDAC1 (0.41) | DRD2DRD3PAK1CNR1CNR2 | |
| SCHEMBL2091162 | 0.66 | HTR6 (0.34) | IRAK4PHGDH | |
| SCHEMBL2095123 | 0.63 | PCSK9 (0.42) | — | |
| SCHEMBL27644895 | 0.63 | NPC1 (0.52) | SCD | |
| SCHEMBL27666318 | 0.62 | GRM2 (0.44) | DRD2 | |
| SCHEMBL2090674 | 0.61 | IDH2 (0.39) | TRPV1PHGDH | |
| SCHEMBL31342940 | 0.60 | PHGDH (0.47) | DRD2DRD3PAK1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |