Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 5/20 | 0.49 |
| ▸ | GABBR1 | Q9UBS5 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665316 | 0.85 | ESR1 (0.50) | CYP2C9LMNACYP2D6CYP2C19CYP1A2 | |
| SCHEMBL28761407 | 0.85 | GRIK1 (0.48) | LMNAGRIK1GRIK2SLC1A3SLC1A2 | |
| SCHEMBL5322716 | 0.85 | GRM2 (0.57) | GABBR2GABBR1CYP2D6CYP1A2GRIK1 | |
| SCHEMBL27644089 | 0.84 | GRIK1 (0.47) | GABBR2GABBR1GRIK1GRIK2SLC1A3 | |
| SCHEMBL27644257 | 0.83 | L3MBTL1 (0.44) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL27644305 | 0.82 | GRIK1 (0.49) | LMNAMEN1KMT2ATSHRGRIK1 | |
| SCHEMBL4994829 | 0.81 | GABBR2 (0.54) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL27665527 | 0.80 | GRM8 (0.50) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27644669 | 0.80 | GRIK1 (0.45) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL27665762 | 0.78 | TDP1 (0.50) | LMNAKMT2ACYP1A2ADORA3NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |