Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18806057 | 0.82 | THRB (0.45) | ERN1THRBBACE1 | |
| SCHEMBL28295437 | 0.81 | ABCG2 (0.45) | THRBTUBB1HTR1AABCG2 | |
| SCHEMBL22353015 | 0.81 | CYP1A2 (0.51) | ERN1THRBBACE1 | |
| SCHEMBL22173894 | 0.81 | KDM4E (0.46) | ERN1THRBBACE1 | |
| SCHEMBL25876143 | 0.80 | ADORA3 (0.41) | THRBBACE1GAATUBB4ATUBB | |
| SCHEMBL25855617 | 0.80 | THRB (0.36) | THRBBACE1TUBB4ATUBBTUBA3C | |
| SCHEMBL27643866 | 0.79 | HDAC4 (0.52) | ERN1THRBHDAC4HDAC2HDAC8 | |
| SCHEMBL21589321 | 0.78 | THRB (0.41) | ERN1THRBBACE1 | |
| SCHEMBL19881858 | 0.78 | PLAU (0.50) | ERN1THRBGAA | |
| SCHEMBL25855189 | 0.77 | KMT2A (0.35) | THRBBACE1GAATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100404479-C | Method for producing aromatic unsaturated compound | SUMITOMO CHEMICAL CO (JP) | 2008-07-23 | — | — | CN | disclosed |
| CN-1871188-A | Method for producing aromatic unsaturated compound | SUMITOMO CHEMICAL CO (JP) | 2006-11-29 | — | — | CN | disclosed |