Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.33 |
| ▸ | CDK9 | P50750 | 3/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800073 | 0.84 | HTR6 (0.65) | HTR6CCNT1CDK9PDK4 | |
| Hydrochloric Acid SCHEMBL2798989 | 0.72 | HTR6 (0.58) | HTR6CYP2C19DRD2 | |
| Tert-Butyl Formate SCHEMBL27644854 | 0.72 | HTR6 (0.48) | HTR6DRD2 | |
| SCHEMBL21714219 | 0.72 | CCNT1 (0.51) | HTR6CCNT1CDK9 | |
| SCHEMBL30134968 | 0.69 | PIK3C3 (0.45) | HTR6PIK3C3CYP2C19 | |
| SCHEMBL20919965 | 0.69 | HTR6 (0.52) | HTR6CYP2C19DRD2 | |
| SCHEMBL2064011 | 0.68 | HTR6 (0.71) | HTR6DRD2 | |
| SCHEMBL29952621 | 0.68 | CYP2C19 (0.55) | HTR6PIK3C3CYP2C19DRD2ALDH1A1 | |
| SCHEMBL21456788 | 0.67 | CYP2C19 (0.49) | HTR6PIK3C3CYP2C19DRD2PKM | |
| SCHEMBL27795727 | 0.67 | CYP2C19 (0.45) | HTR6CYP2C19ALDH1A1PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882347-A | AKT protein kinase inhibitors | ARRAY BIOPHARMA INC (US) | 2006-12-20 | — | — | CN | disclosed |