Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 13/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298035 | 0.88 | MMP13 (0.64) | MMP13MEN1KMT2A | |
| SCHEMBL27645085 | 0.85 | MMP13 (0.51) | MMP13APPHDAC1HDAC2HDAC11 | |
| SCHEMBL30129021 | 0.83 | GRK2 (0.49) | APPHDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL27660577 | 0.78 | MMP13 (0.63) | MMP13HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL6302762 | 0.75 | MMP13 (0.65) | MMP13HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL6830594 | 0.75 | MMP13 (0.68) | MMP13SMN1; SMN2 | |
| SCHEMBL23520500 | 0.75 | MMP13 (0.65) | MMP13 | |
| SCHEMBL6014176 | 0.74 | GRK2 (0.65) | MMP13 | |
| SCHEMBL2619423 | 0.73 | SLC2A1 (0.49) | MMP13APPHDAC1HDAC2HDAC11 | |
| SCHEMBL6297376 | 0.73 | MMP13 (0.63) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1738806-A | Oxo-azabicyclic compounds | WARNER LAMBERT CO (US) | 2006-02-22 | — | — | CN | disclosed |