Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 11/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128609 | 0.85 | GRK2 (0.49) | GRK2P2RX3APPHDAC1HDAC2 | |
| SCHEMBL30128619 | 0.85 | GRK2 (0.52) | GRK2P2RX3 | |
| SCHEMBL30128680 | 0.85 | MCL1 (0.50) | GRK2P2RX3APPHDAC1HDAC2 | |
| SCHEMBL30128600 | 0.85 | TRPA1 (0.52) | GRK2P2RX3 | |
| SCHEMBL27645087 | 0.83 | MMP13 (0.51) | P2RX3APPHDAC1HDAC2HDAC11 | |
| SCHEMBL30128753 | 0.81 | P2RX3 (0.61) | P2RX3 | |
| SCHEMBL28389854 | 0.81 | SMN1; SMN2 (0.53) | GRK2HTT | |
| SCHEMBL30128668 | 0.81 | L3MBTL1 (0.58) | GRK2P2RX3HTT | |
| SCHEMBL30128824 | 0.77 | PDE5A (0.51) | GRK2APPHDAC1HDAC2HDAC11 | |
| SCHEMBL6014176 | 0.75 | GRK2 (0.65) | GRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116552-B | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2022-10-11 | — | — | CN | disclosed |