Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666211 | 1.00 | NMT1 (0.44) | NMT1F10GRM2KCNH2ADRB2 | |
| SCHEMBL28761502 | 0.87 | KCNH2 (0.52) | NMT1F10KCNH2ADRB2NCF1 | |
| SCHEMBL27644982 | 0.84 | GRM2 (0.42) | NMT1GRM2CHRM4ACHEDRD2 | |
| SCHEMBL2091985 | 0.83 | GRM2 (0.45) | NMT1GRM2CHRM4DRD2DRD4 | |
| SCHEMBL27645178 | 0.82 | ADRB2 (0.51) | NMT1F10KCNH2ADRB2NCF1 | |
| SCHEMBL2088412 | 0.82 | GRM2 (0.41) | NMT1GRM2CHRM4ACHEDRD2 | |
| SCHEMBL2093955 | 0.82 | GRM2 (0.41) | NMT1GRM2CHRM4ACHEDRD2 | |
| SCHEMBL28761490 | 0.80 | NMT1 (0.49) | NMT1KCNH2ADRB2NCF1MAPT | |
| SCHEMBL2097669 | 0.80 | GRM2 (0.44) | GRM2CHRM4DRD2DRD4DRD3 | |
| SCHEMBL2093386 | 0.76 | GRM2 (0.42) | GRM2KCNH2CHRM4DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |