Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645178 | 0.95 | ADRB2 (0.51) | KCNH2ADRB2NCF1ACHENMT1 | |
| SCHEMBL2093497 | 0.87 | NMT1 (0.42) | KCNH2ACHENMT1DRD2DRD3 | |
| SCHEMBL27645112 | 0.87 | NMT1 (0.43) | KCNH2ADRB2NCF1ACHENMT1 | |
| SCHEMBL27645182 | 0.87 | NMT1 (0.44) | KCNH2ADRB2NCF1ACHENMT1 | |
| SCHEMBL27666211 | 0.87 | NMT1 (0.44) | KCNH2ADRB2NCF1ACHENMT1 | |
| SCHEMBL2089595 | 0.86 | NMT1 (0.46) | KCNH2ADRB2NCF1ACHENMT1 | |
| SCHEMBL28761490 | 0.82 | NMT1 (0.49) | KCNH2ADRB2NCF1ACHENMT1 | |
| SCHEMBL2096547 | 0.79 | SLC18A3 (0.41) | ACHENMT1SLC18A3PDE10A | |
| SCHEMBL27666325 | 0.78 | KCNH2 (0.73) | KCNH2ADRB2NCF1DRD2DRD3 | |
| SCHEMBL6186822 | 0.77 | ADRB2 (0.62) | KCNH2ADRB2NCF1F10DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |