Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095973 | 0.82 | ALDH1A1 (0.60) | EPHX2NPC1RAB9AMAPTHTT | |
| SCHEMBL2091276 | 0.81 | EPHX2 (0.47) | EPHX2NPC1RAB9ATRPV1KMT2A | |
| SCHEMBL2096310 | 0.81 | EPHX2 (0.76) | EPHX2NPC1RAB9AMAPTTRPV1 | |
| SCHEMBL23213602 | 0.75 | EPHX2 (0.45) | EPHX2NPC1RAB9AMAPTTRPV1 | |
| SCHEMBL3173854 | 0.74 | HDAC3 (0.41) | EPHX2NPC1RAB9AMAPT | |
| SCHEMBL29556169 | 0.74 | EPHX2 (0.56) | EPHX2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL30104928 | 0.74 | ALDH1A1 (0.49) | EPHX2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL20357431 | 0.72 | FFAR4 (0.43) | EPHX2MAPTKMT2AHTTALDH1A1 | |
| SCHEMBL2094856 | 0.71 | MAPT (0.38) | EPHX2NPC1RAB9AMAPT | |
| SCHEMBL2091142 | 0.71 | L3MBTL1 (0.42) | EPHX2NPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |