Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.61 |
| ▸ | PARP1 | P09874 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180654 | 0.87 | KMT2A (0.58) | PARP10KMT2AMAPTTDP1MEN1 | |
| SCHEMBL23488123 | 0.80 | PARP10 (0.69) | PARP10PARP1KMT2AMAPTTDP1 | |
| SCHEMBL27645371 | 0.79 | MAPT (0.50) | PARP10KMT2AMAPTTDP1MEN1 | |
| SCHEMBL2755026 | 0.77 | KMT2A (0.68) | PARP10KMT2AMAPTTDP1MEN1 | |
| SCHEMBL6643945 | 0.77 | ESR1 (0.69) | PARP10KMT2AMAPTTDP1MEN1 | |
| SCHEMBL23486305 | 0.76 | PARP10 (1.00) | PARP10PARP1KMT2AMAPTTDP1 | |
| SCHEMBL27986240 | 0.75 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1MEN1 | |
| SCHEMBL10179685 | 0.75 | KMT2A (0.56) | PARP10KMT2AMAPTTDP1MEN1 | |
| SCHEMBL11272755 | 0.74 | PARP10 (0.89) | PARP10PARP1KMT2AMAPTTDP1 | |
| SCHEMBL28423662 | 0.74 | KMT2A (0.59) | PARP10KMT2AMAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1867551-B | Phenyl or pyridyl amide compounds as prostaglandin E2 antagonists | RAQUALIA PHARMA INC | 2013-09-11 | — | — | CN | disclosed |
| CN-1867551-A | Phenyl or pyridyl amide compounds as prostaglandin E2 antagonists | PFIZER (US) | 2006-11-22 | — | — | CN | disclosed |