Sugi Predict

Sugi Predict / Compounds / SCHEMBL10179685

SCHEMBL10179685

SCHEMBL10179685

O=C(Oc1cc(F)c(F)c(F)c1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 11/20 0.56
▸ MAPT P10636 6/20 0.56
▸ MEN1 O00255 3/20 0.56
▸ TDP1 Q9NUW8 2/20 0.56
▸ PARP10 Q53GL7 1/20 0.51
▸ NSD2 O96028 1/20 0.51
▸ ALDH1A1 P00352 4/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ PKM P14618 1/20 0.49
▸ F2 P00734 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ RAB9A P51151 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ CA12 O43570 2/20 0.45
▸ CA9 Q16790 2/20 0.45
▸ POLB P06746 1/20 0.45
▸ ESR1 P03372 1/20 0.45
▸ ESR2 Q92731 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.44
▸ GLA P06280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18937909 0.89 KMT2A (0.49) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL17431972 0.86 KMT2A (0.53) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL2755026 0.84 KMT2A (0.68) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL29653765 0.84 SENP1 (0.46) KMT2AMEN1TDP1NSD2ALDH1A1
SCHEMBL10179765 0.84 KMT2A (0.64) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL28014628 0.83 MAPT (0.49) KMT2AMAPTMEN1TDP1NSD2
SCHEMBL10180654 0.83 KMT2A (0.58) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL28130093 0.83 MAPT (0.54) KMT2AMAPTMEN1TDP1NSD2
SCHEMBL16426509 0.82 RAB9A (0.43) KMT2AMAPTMEN1LMNARAB9A
SCHEMBL28518358 0.82 CES2 (0.39) KMT2AMAPTMEN1TDP1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170357131-A1 LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2017-12-14 — — US disclosed
US-20170351130-A1 LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2017-12-07 — — US disclosed
US-20170343847-A1 LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2017-11-30 — — US disclosed
US-20170342324-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2017-11-30 — — US disclosed
US-20170327741-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2017-11-16 — — US disclosed
US-9758727-B2 Bimesogenic compounds and mesogenic media MERCK PATENT GMBH (DE) 2017-09-12 — — US disclosed
US-9752075-B2 Mesogenic media and liquid crystal display MERCK PATENT GMBH (DE) 2017-09-05 — — US disclosed
US-20170210990-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2017-07-27 — — US disclosed
US-20170190971-A1 MESOGENIC MEDIA AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2017-07-06 — — US disclosed
US-9644144-B2 Bimesogenic compounds and mesogenic media MERCK PATENT GMBH (DE) 2017-05-09 — — US disclosed
US-20150210921-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2015-07-30 — — US disclosed
US-20150203756-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2015-07-23 — — US disclosed
US-20150203755-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2015-07-23 — — US disclosed
US-20150175883-A1 Bimesogenic Compounds and Mesogenic Media MERCK PATENT GMBH (DE) 2015-06-25 — — US disclosed
US-20150175886-A1 MESOGENIC MEDIA AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2015-06-25 — — US disclosed
US-20150090935-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2015-04-02 — — US disclosed
CN-104112870-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2014-10-22 — — CN disclosed
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 — — US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 — — US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210921-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA SP1, FOXM1, S100A11 KMT2A 2102/4885MAPT 1228/4885MEN1 40/4885
US-20150175883-A1 Bimesogenic Compounds and Mesogenic Media SP1, FOXM1, S100A11 KMT2A 2102/4885MAPT 1228/4885MEN1 40/4885
US-20150203756-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA SP1, FOXM1, S100A11 KMT2A 2102/4885MAPT 1228/4885MEN1 40/4885
US-20170327741-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA SP1, FOXM1, S100A11 KMT2A 2102/4885MAPT 1228/4885MEN1 40/4885
US-20170210990-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA SP1, FOXM1, S100A11 KMT2A 2102/4885MAPT 1228/4885MEN1 40/4885
US-20170342324-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MTX1, S100A11, MCRS1 KMT2A 3390/4885MAPT 2175/4885MEN1 7/4885
US-20150203755-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA SP1, FOXM1, S100A11 KMT2A 2102/4885MAPT 1228/4885MEN1 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.