Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241158 | 0.89 | MTNR1A (0.40) | MTNR1AMTNR1BFGFR1FGFR2FGFR4 | |
| SCHEMBL4339833 | 0.85 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL244699 | 0.82 | MAPT (0.37) | MTNR1AMTNR1B | |
| SCHEMBL5529306 | 0.81 | MAPT (0.36) | MTNR1AMTNR1B | |
| SCHEMBL5526466 | 0.81 | MAPT (0.36) | MTNR1AMTNR1B | |
| SCHEMBL5529309 | 0.80 | MAPT (0.36) | MTNR1AMTNR1B | |
| Water SCHEMBL20853627 | 0.80 | MAPT (0.36) | MTNR1AMTNR1B | |
| SCHEMBL20853803 | 0.76 | MAPT (0.43) | MTNR1AMTNR1B | |
| SCHEMBL25118360 | 0.76 | MTNR1B (0.57) | MTNR1AMTNR1B | |
| SCHEMBL30060301 | 0.76 | MTNR1B (0.57) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799537-B2 | Cholesterol measuring reagent containing a cholesterol esterase | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| EP-1818412-B1 | METHOD OF MEASURING CHOLESTEROL IN REMNANT-LIKE LIPOPROTEINS | OTSUKA PHARMA CO LTD (JP) | 2010-04-14 | — | — | EP | disclosed |
| US-20080268461-A1 | Using lipoprotein lipase to cholesterol esterase ratios as evaluative tools in diagnosis/prognosis of arteriosclerosis | JIMRO CO., LTD. (JP) | 2008-10-30 | — | — | US | disclosed |
| EP-1818412-A1 | METHOD OF MEASURING CHOLESTEROL IN REMNANT-LIKE LIPOPROTEINS | Jimro Co., Ltd. (JP) | 2007-08-15 | — | — | EP | disclosed |