SCHEMBL2764558

SCHEMBL2764558

Cc1cc(C)n(C(n2nc(C)cc2C)(n2nc(C)cc2C)[Mn](Cl)Cl)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
GLS O94925 1/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C9 P11712 2/20 0.32
MEN1 O00255 2/20 0.32
ALOX15 P16050 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
ENPP3 O14638 1/20 0.32
ALPL P05186 1/20 0.32
XIAP P98170 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2766528 0.73 KDM4E (0.43) KDM4EALDH1A1GAAHTTTSHR
SCHEMBL2733622 0.73 ALDH1A1 (0.41) KDM4EALDH1A1GLAGLSGAA
SCHEMBL2454430 0.73 ALDH1A1 (0.45) KDM4EALDH1A1GLAGLSGAA
SCHEMBL3423392 0.71 KDM4E (0.39) KDM4EALDH1A1GLAGLSGAA
SCHEMBL4464474 0.71 ALDH1A1 (0.39) KDM4EALDH1A1GLAGLSGAA
SCHEMBL6903297 0.71 ALDH1A1 (0.39) KDM4EALDH1A1GLAGLSGAA
SCHEMBL6453093 0.71 ALDH1A1 (0.39) KDM4EALDH1A1GLAGLSGAA
SCHEMBL715163 0.71 KDM4E (0.35) KDM4EALDH1A1GLAGLSGAA
SCHEMBL2766388 0.71 KDM4E (0.39) KDM4EALDH1A1GLAGLSGAA
SCHEMBL2765830 0.69 KDM4E (0.37) KDM4EALDH1A1HTTTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266911-B1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL CO (JP) 2010-04-14 EP disclosed
US-6881802-B2 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-04-19 US disclosed
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-02-13 US disclosed
EP-1266911-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer BRAP, MCM4, BOLA2; BOLA2B KDM4E 2623/4885ALDH1A1 3572/4885GLA 3982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.