SCHEMBL2765830

SCHEMBL2765830

Cc1cc(C23CC4CC(CC(C4)C2)C3)nn1C(n1nc(C23CC4CC(CC(C4)C2)C3)cc1C)(n1nc(C23CC4CC(CC(C4)C2)C3)cc1C)[Mn](Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
TSHR P16473 2/20 0.37
ALDH1A1 P00352 2/20 0.33
HTT P42858 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HSD11B1 P28845 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30
HRH4 Q9H3N8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2765963 0.80 KDM4E (0.37) KDM4ETSHRALDH1A1HTTMEN1
SCHEMBL14189312 0.73 HTT (0.48) KDM4ETSHRALDH1A1HTTMEN1
SCHEMBL2764890 0.73 KDM4E (0.33) KDM4E
SCHEMBL2767113 0.71 ALDH1A1 (0.38) KDM4EALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL2765827 0.70 KDM4E (0.38) KDM4ETSHRALDH1A1HTTMEN1
SCHEMBL2764558 0.69 KDM4E (0.39) KDM4ETSHRALDH1A1HTTMEN1
Butadiene SCHEMBL2764888 0.65 KDM4E (0.36) KDM4ETSHRALDH1A1HTTMEN1
SCHEMBL2571479 0.59 RAB9A (0.49) KDM4ETSHRALDH1A1MEN1KMT2A
SCHEMBL5027179 0.59 KDM4E (0.44) KDM4ETSHRALDH1A1HTTSMN1; SMN2
SCHEMBL26964747 0.59 SMN1; SMN2 (0.31) SMN1; SMN2GPR55HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266911-B1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL CO (JP) 2010-04-14 EP disclosed
US-6881802-B2 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-04-19 US disclosed
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-02-13 US disclosed
EP-1266911-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer BRAP, MCM4, BOLA2; BOLA2B KDM4E 2623/4885TSHR 4795/4885ALDH1A1 3572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.