Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808287 | 0.85 | TSHR (0.55) | TSHRSRD5A2ALDH1A1CASP1SMN1; SMN2 | |
| SCHEMBL15855876 | 0.85 | TSHR (0.61) | TSHRSRD5A2ALDH1A1MAPTCASP1 | |
| SCHEMBL5248866 | 0.82 | KDM4E (0.48) | TSHRSRD5A2ALDH1A1MAPTPOLB | |
| SCHEMBL30162746 | 0.82 | TSHR (0.68) | TSHRSRD5A2ALDH1A1MAPTCASP1 | |
| SCHEMBL68294 | 0.82 | TSHR (0.68) | TSHRSRD5A2ALDH1A1MAPTCASP1 | |
| Hydrochloric Acid SCHEMBL1681859 | 0.80 | TSHR (0.65) | TSHRSRD5A2ALDH1A1MAPTCASP1 | |
| Hydrochloric Acid SCHEMBL943311 | 0.80 | TSHR (0.65) | TSHRSRD5A2ALDH1A1MAPTCASP1 | |
| SCHEMBL22991263 | 0.80 | ALDH1A1 (0.54) | TSHRALDH1A1MAPTCASP1SMN1; SMN2 | |
| SCHEMBL22335212 | 0.79 | CDC25B (0.46) | TSHRALDH1A1MAPTCASP1SMN1; SMN2 | |
| SCHEMBL5900757 | 0.79 | KMT2A (0.50) | ALDH1A1PLAUF2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1753683-B | Ophthalmic formulation for the prevention and treatment of ocular conditions | CHAKSHU RES INC | 2010-05-26 | — | — | CN | claimed |
| CN-1753683-A | Ophthalmic formulation for the prevention and treatment of ocular conditions | CHAKSHU RES INC (US) | 2006-03-29 | — | — | CN | claimed |
| CN-1753683-B | Ophthalmic formulation for the prevention and treatment of ocular conditions | CHAKSHU RES INC | 2010-05-26 | — | — | CN | disclosed |
| CN-101304727-A | Treatment of disorders associated with the presence of macromolecular aggregates, particularly ophthalmic diseases | CHAKSHU RES INC (US) | 2008-11-12 | — | — | CN | disclosed |
| CN-101262886-A | Formulation and method for administration of ophthalmologically active agents | CHAKSHU RES INC (US) | 2008-09-10 | — | — | CN | disclosed |
| CN-1753683-A | Ophthalmic formulation for the prevention and treatment of ocular conditions | CHAKSHU RES INC (US) | 2006-03-29 | — | — | CN | disclosed |