Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3995292 | 0.89 | ALDH1A1 (0.54) | USP2TSHRHTTACHEDRD2 | |
| SCHEMBL4003775 | 0.78 | CCR3 (0.59) | DRD2HTR2A | |
| SCHEMBL4002190 | 0.76 | CCR3 (0.42) | USP2TSHRHTTDRD2HTR2A | |
| SCHEMBL4001388 | 0.76 | CCR3 (0.40) | DRD2OPRM1HTR2A | |
| SCHEMBL3997513 | 0.75 | CCR3 (0.50) | — | |
| SCHEMBL13797764 | 0.74 | CCR3 (0.45) | TSHRDRD2DRD4TMEM97HTR2A | |
| SCHEMBL4001652 | 0.74 | CCR3 (0.47) | — | |
| SCHEMBL13797763 | 0.74 | CCR3 (0.42) | DRD2 | |
| SCHEMBL13797758 | 0.74 | CCR3 (0.56) | DRD2HTR2A | |
| SCHEMBL13797767 | 0.72 | CCR3 (0.49) | USP2DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882565-A | Novel piperidine-substituted indoles-or hetero-derivatives thereof and their use as modulators of chemokine receptor (CCR-3) | BOEHRINGER INGELHEIM INT (DE) | 2006-12-20 | — | — | CN | disclosed |