SCHEMBL27645804

SCHEMBL27645804

C=C(C(=O)O)C(=O)O.CCc1ccccc1CC

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.44
GABRB2 P47870 2/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.43
CLCN2 P51788 1/20 0.41
AKR1B1 P15121 1/20 0.40
CTBP2 P56545 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
TP53 P04637 2/20 0.39
CACNA1C Q13936 1/20 0.39
SCN5A Q14524 1/20 0.39
GAA P10253 1/20 0.38
GLA P06280 1/20 0.38
TSHR P16473 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
EGFR P00533 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL28077388 0.84 TP53 (0.61) ALDH1A1MAPTAKR1B1CES2CES1
Bicarbonate SCHEMBL29051241 0.83 GABRA1 (0.55) GABRA1GABRB2ALDH1A1MAPTCLCN2
Bicarbonate SCHEMBL14635340 0.83 GABRA1 (0.55) GABRA1GABRB2ALDH1A1MAPTCLCN2
Hydrogen Peroxide SCHEMBL10890655 0.83 GABRA1 (0.60) GABRA1GABRB2ALDH1A1MAPTCLCN2
Hydrogen Peroxide SCHEMBL11205186 0.83 GABRA1 (0.60) GABRA1GABRB2ALDH1A1MAPTCLCN2
SCHEMBL6430884 0.82 CLCN2 (0.42) GABRA1GABRB2ALDH1A1MAPTCLCN2
SCHEMBL7336703 0.81 AKR1B1 (0.41) GABRA1GABRB2ALDH1A1MAPTCLCN2
Acetic Acid SCHEMBL1724578 0.80 GABRA1 (0.52) GABRA1GABRB2ALDH1A1CLCN2AKR1B1
Benzene SCHEMBL3122858 0.80 TP53 (0.56) GABRA1GABRB2MAPTCLCN2AKR1B1
Benzene SCHEMBL11603070 0.80 TP53 (0.56) GABRA1GABRB2MAPTCLCN2AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1917847-A Metal oxide particles as radical scavengers for use in sunscreen and cosmetic compositions OXONICA LTD (GB) 2007-02-21 CN disclosed