Ethylbenzene

Ethylbenzene

SCHEMBL28077388

C=C(C(=O)O)C(=O)O.CCc1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.61
ALDH1A1 P00352 6/20 0.48
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
KDM4E B2RXH2 2/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
AKR1B1 P15121 1/20 0.43
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
RAB9A P51151 1/20 0.42
MAPT P10636 1/20 0.42
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
BCL2 P10415 1/20 0.41
TAS2R14 Q9NYV8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL27804631 0.87 TP53 (0.61) TP53ALDH1A1PPARGPPARAKDM4E
SCHEMBL27645804 0.84 GABRA1 (0.44) TP53ALDH1A1CES2CES1AKR1B1
Ethylbenzene SCHEMBL27323077 0.84 TP53 (0.78) TP53ALDH1A1PPARGPPARACES2
Ethylbenzene SCHEMBL6235014 0.82 TP53 (0.54) TP53ALDH1A1PPARGPPARAKDM4E
Ethylbenzene SCHEMBL28436435 0.81 TP53 (0.74) TP53ALDH1A1PPARGPPARACES2
Ethylbenzene SCHEMBL27596106 0.81 TP53 (0.74) TP53ALDH1A1PPARGPPARACES2
Ethylbenzene SCHEMBL10979046 0.81 TP53 (0.74) TP53ALDH1A1PPARGPPARACES2
Ethylbenzene SCHEMBL28754507 0.81 TP53 (0.74) TP53ALDH1A1PPARGPPARASMN1; SMN2
Ethylbenzene SCHEMBL27373771 0.81 TP53 (0.82) TP53ALDH1A1PPARGPPARACES2
Ethylbenzene SCHEMBL216251 0.81 TP53 (0.93) TP53ALDH1A1PPARGPPARACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105837714-A METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER 东邦钛株式会社 2016-08-10 CN disclosed