Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28758489 | 0.88 | TSHR (0.39) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL4758984 | 0.83 | TSHR (0.42) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL27895655 | 0.82 | TSHR (0.41) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL3100065 | 0.82 | TSHR (0.41) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL11703874 | 0.81 | TSHR (0.40) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL305556 | 0.81 | TSHR (0.40) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL27666954 | 0.80 | TSHR (0.42) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL27689253 | 0.80 | TSHR (0.39) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL27666953 | 0.79 | CYP1A2 (0.36) | TSHRLMNAHTTCYP3A4SMN1; SMN2 | |
| SCHEMBL15158116 | 0.77 | TSHR (0.37) | TSHRLMNAHTTCYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100384895-C | Actinic-energy-ray-curable composition for optical material | TOAGOSEI CO LTD (JP) | 2008-04-30 | — | — | CN | claimed |
| CN-100384895-C | Actinic-energy-ray-curable composition for optical material | TOAGOSEI CO LTD (JP) | 2008-04-30 | — | — | CN | disclosed |
| CN-1875041-A | Actinic-energy-ray-curable composition for optical material | TOAGOSEI CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |