Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703874 | 0.89 | TSHR (0.40) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL27645828 | 0.83 | TSHR (0.42) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL27895655 | 0.82 | TSHR (0.41) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL3100065 | 0.82 | TSHR (0.41) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL305556 | 0.81 | TSHR (0.40) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL7084293 | 0.80 | ALDH1A1 (0.34) | TSHRLMNAHTTGAASMN1; SMN2 | |
| SCHEMBL27689253 | 0.80 | TSHR (0.39) | TSHRLMNAHTTCYP3A4GAA | |
| SCHEMBL330418 | 0.79 | HSD17B10 (0.35) | TSHRCYP3A4SMN1; SMN2KMT2AGLA | |
| SCHEMBL29489300 | 0.79 | HSD17B10 (0.35) | TSHRCYP3A4SMN1; SMN2KMT2AGLA | |
| SCHEMBL5698005 | 0.77 | ALDH1A1 (0.34) | TSHRLMNAHTTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080145545-A1 | METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM | CITIBANK, N.A., AS COLLATERAL AGENT | 2008-06-19 | — | — | US | disclosed |
| WO-2008073534-A1 | METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-06-19 | — | — | WO | disclosed |
| US-7271283-B2 | High refractive index, UV-curable monomers and coating compositions prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 2007-09-18 | — | — | US | disclosed |
| EP-1512704-A1 | High refractive index, UV-curable monomers and coating compositions prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 2005-03-09 | — | — | EP | disclosed |
| US-20050049376-A1 | High refractive index, uv-curable monomers and coating compositions prepared therefrom | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | disclosed |
| EP-0735062-B1 | ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET | MITSUBISHI RAYON CO (JP) | 2002-01-30 | — | — | EP | disclosed |
| US-6206550-B1 | BACKLIGHT WITH LENS PORTION MADE FROM A CURABLE COMPOSITION WHICH INCLUDES A BIS(4-(METH)ACRYLOYL-THIOPHENYL) SULFIDE AND (METH)ACRYLATES; HIGH BRIGHTNESS-ENHANCING EFFECT ON LENSES OF PROJECTION TVS AND STEREOSCOPIC PHOTOGRAPHY. | MITSUBISHI RAYON COMPANY LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0952466-A2 | Lens sheet | MITSUBISHI RAYON CO., LTD. (JP) | 1999-10-27 | — | — | EP | disclosed |
| US-5969867-A | ACRYLIC ESTERS | MITSUBISHI RAYON COMPANY LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0735062-A1 | ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET | MITSUBISHI RAYON CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049376-A1 | High refractive index, uv-curable monomers and coating compositions prepared therefrom | MACF1, WASF2, THEM6 | TSHR 4739/4885LMNA 2007/4885HTT 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.