SCHEMBL305556

SCHEMBL305556

C=C(C)C(=O)Oc1c(OCC)cc(C(C)(C)c2cc(OCC)c(OC(=O)C(=C)C)c(OCC)c2OCC)c(OCC)c1OCC

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
CYP3A4 P08684 1/20 0.36
GAA P10253 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GLA P06280 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NCOA1 Q15788 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15158116 0.95 TSHR (0.37) TSHRMEN1KMT2ALMNAHTT
SCHEMBL66400 0.93 TSHR (0.35) TSHRMEN1KMT2ALMNAHTT
SCHEMBL29771136 0.93 TSHR (0.35) TSHRMEN1KMT2ALMNAHTT
SCHEMBL29114642 0.88 MEN1 (0.36) TSHRMEN1KMT2AHTTALDH1A1
SCHEMBL29771328 0.88 MEN1 (0.36) TSHRMEN1KMT2AHTTALDH1A1
SCHEMBL65695 0.88 MEN1 (0.36) TSHRMEN1KMT2AHTTALDH1A1
SCHEMBL392038 0.87 MEN1 (0.34) TSHRMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL32674605 0.86 EGFR (0.33) TSHRCYP1A2CYP2C9CYP2C19
SCHEMBL6472692 0.86 TSHR (0.36) TSHRKMT2AHTTSMN1; SMN2ALDH1A1
SCHEMBL6292049 0.85 THRB (0.42) TSHRMEN1KMT2ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11992538-B2 Polymerizable dental composition based on condensed silanes VOCO GMBH (DE) 2024-05-28 US claimed
EP-4306099-A1 METHOD FOR PRODUCING DENTAL MILL BLANKS VOCO GmbH (DE) 2024-01-17 EP claimed
US-20240008963-A1 PROCESS FOR THE PRODUCTION OF DENTAL MILLING BLANKS VOCO GMBH (DE) 2024-01-11 US claimed
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2021-02-25 US claimed
EP-2623087-B1 Dental composite materials containing tricyclic plasticisers VOCO GMBH (DE) 2019-07-17 EP claimed
EP-2623086-B1 Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. VOCO GMBH (DE) 2019-07-10 EP claimed
US-9314408-B2 Dental composite materials comprising tricyclic plasticizers VOCO GMBH (DE) 2016-04-19 US claimed
US-20130203884-A1 DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS VOCO GMBH (DE) 2013-08-08 US claimed
US-7799844-B2 Active energy beam-curable composition for optical material TOAGOSEI CO., LTD. (JP) 2010-09-21 US claimed
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP claimed
US-6206550-B1 BACKLIGHT WITH LENS PORTION MADE FROM A CURABLE COMPOSITION WHICH INCLUDES A BIS(4-(METH)ACRYLOYL-THIOPHENYL) SULFIDE AND (METH)ACRYLATES; HIGH BRIGHTNESS-ENHANCING EFFECT ON LENSES OF PROJECTION TVS AND STEREOSCOPIC PHOTOGRAPHY. MITSUBISHI RAYON COMPANY LTD. (JP) 2001-03-27 US claimed
US-5969867-A ACRYLIC ESTERS MITSUBISHI RAYON COMPANY LTD. (JP) 1999-10-19 US claimed
EP-0735062-A1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO., LTD. (JP) 1996-10-02 EP claimed
US-4647638-A Novel organophosphate and adhesive comprising it NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-03-03 US claimed
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
US-20250032366-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-01-30 US disclosed
WO-2024253204-A1 CURABLE DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-12-12 WO disclosed
US-4388421-A PRIMERS LION CORPORATION (JP) 1983-06-14 US disclosed
US-4383052-A 1-Methacryloxyethane-1,1-diphosphonic acid and its salts and dental adhesive composition containing same LION CORPORATION (JP) 1983-05-10 US disclosed
US-4055542-A PEROXIDE THREE BOND CO., LTD. (JA) 1977-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992538-B2 Polymerizable dental composition based on condensed silanes NCAPH, RCC1, NCAPD2 TSHR 4596/4885MEN1 3233/4885KMT2A 628/4885
US-20250032366-A1 DENTAL CURABLE COMPOSITION H1-0, COL1A1, CHAF1B TSHR 4352/4885MEN1 353/4885KMT2A 2851/4885
US-20130203884-A1 DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS CAD, PBRM1, PCBP1 TSHR 3986/4885MEN1 3804/4885KMT2A 2690/4885
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES NCAPH, RCC1, NCAPD2 TSHR 4596/4885MEN1 3233/4885KMT2A 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.