Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27614960 | 0.86 | DNM1 (0.60) | DNM1CHRM2MEN1KMT2ABCHE | |
| SCHEMBL2924382 | 0.82 | DNM1 (0.62) | DNM1CHRM2MEN1KMT2ABCHE | |
| SCHEMBL1134127 | 0.82 | CHRM2 (0.74) | CHRM2MEN1KMT2ABCHEHDAC1 | |
| SCHEMBL4814984 | 0.81 | CHRM2 (0.60) | DNM1CHRM2MEN1KMT2ABCHE | |
| SCHEMBL21740355 | 0.81 | DNM1 (0.61) | DNM1CHRM2MEN1KMT2ABCHE | |
| SCHEMBL7048773 | 0.80 | DNM1 (0.54) | DNM1CHRM2MEN1KMT2ABCHE | |
| Hydrochloric Acid SCHEMBL6122475 | 0.80 | CHRM2 (0.72) | CHRM2MEN1KMT2ABCHEHDAC1 | |
| SCHEMBL13995736 | 0.80 | CHRM2 (0.59) | DNM1CHRM2MEN1KMT2ABCHE | |
| SCHEMBL168266 | 0.79 | DNM1 (0.62) | DNM1CHRM2MEN1KMT2ABCHE | |
| SCHEMBL27302315 | 0.79 | TAAR1 (0.64) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1759095-A | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARM INC (US) | 2006-04-12 | — | — | CN | disclosed |