Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11882343 | 0.86 | MGLL (0.72) | MGLLGAAALOX15ALDH1A1CYP2D6 | |
| SCHEMBL11174876 | 0.83 | CYP3A4 (0.77) | MGLLALDH1A1CYP2D6CYP3A4MAPK1 | |
| SCHEMBL29139529 | 0.83 | MGLL (0.56) | MGLLGAAALOX15ALDH1A1CYP2D6 | |
| SCHEMBL27780514 | 0.81 | MGLL (0.66) | MGLLGAAALOX15ALDH1A1CYP2D6 | |
| SCHEMBL3077817 | 0.79 | SMN1; SMN2 (0.72) | MGLLGAAALOX15ALDH1A1CYP3A4 | |
| SCHEMBL1578826 | 0.79 | ALDH1A1 (0.78) | MGLLGAAALOX15ALDH1A1CYP3A4 | |
| SCHEMBL14040454 | 0.79 | KMT2A (0.55) | MGLLGAAALOX15ALDH1A1CYP2D6 | |
| SCHEMBL10666406 | 0.79 | GAA (0.63) | MGLLGAAALOX15ALDH1A1KMT2A | |
| SCHEMBL14590621 | 0.78 | GAA (0.66) | MGLLGAAALOX15ALDH1A1CYP2D6 | |
| SCHEMBL5104855 | 0.78 | GAA (0.66) | MGLLGAAALOX15ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1812790-A | 3-(1-naphthyl)-2-cyanopropanoic acid derivatives as estrogen receptor | WYETH CORP (US) | 2006-08-02 | — | — | CN | claimed |
| CN-1812790-A | 3-(1-naphthyl)-2-cyanopropanoic acid derivatives as estrogen receptor | WYETH CORP (US) | 2006-08-02 | — | — | CN | disclosed |