Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAX | P61244 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28147393 | 0.85 | BACE1 (0.44) | MAPTBACE1MEN1KMT2APKM | |
| SCHEMBL27664376 | 0.81 | MEN1 (0.47) | MEN1KMT2AL3MBTL1MAOB | |
| SCHEMBL561090 | 0.80 | MAOB (0.56) | MAPTBACE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28171182 | 0.78 | MEN1 (0.47) | MAPTBACE1MEN1KMT2APKM | |
| SCHEMBL27684770 | 0.77 | BACE1 (0.52) | MAPTBACE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL27684080 | 0.76 | MAOB (0.58) | MEN1KMT2AL3MBTL1MAOBPTGES | |
| SCHEMBL19327157 | 0.75 | CTSV (0.46) | MAPTBACE1MEN1KMT2ANPC1 | |
| SCHEMBL1663438 | 0.74 | MEN1 (0.57) | MAPTBACE1MEN1KMT2APKM | |
| SCHEMBL30832846 | 0.74 | MEN1 (0.57) | MAPTBACE1MEN1KMT2APKM | |
| SCHEMBL5024079 | 0.74 | BACE1 (0.46) | MAPTBACE1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003025-A | The preparation method of 1- [2- hydroxyl -3- amino -5- (benzyloxy) phenyl]-ethyl ketone | 天津华津制药有限公司 | 2019-07-12 | — | — | CN | claimed |
| CN-106995414-A | The beta-agonists its preparation method and its purposes in medicament forms of new enantiomeric pure | 贝林格尔英格海姆法玛两合公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-102827097-B | The beta-2-agonists its preparation method of enantiomeric pure and the purposes in medicament forms thereof | 贝林格尔英格海姆法玛两合公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-106146425-A | The beta-agonists its preparation method of new enantiomeric pure and the purposes in medicament forms thereof | 贝林格尔英格海姆法玛两合公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-102827097-A | Novel enantiomerically pure beta-agonists, method for the production and the use thereof in the form of a drug | BOEHRINGER INGELHEIM INT | 2012-12-19 | — | — | CN | disclosed |
| CN-101133039-A | Novel enantiomerically pure beta agonists, method for the production thereof and use thereof in the form of medicaments | BOEHRINGER INGELHEIM INT (DE) | 2008-02-27 | — | — | CN | disclosed |
| CN-101039937-A | Heteroaryl compounds for use as betamimetics in the treatment of respiratory diseases | BOEHRINGER INGELHEIM INT (DE) | 2007-09-19 | — | — | CN | disclosed |
| CN-1984638-A | Inhalable powder formulations comprising enantiomerically pure beta-agonists | BOEHRINGER INGELHEIM INT (DE) | 2007-06-20 | — | — | CN | disclosed |
| CN-1906180-A | New long acting beta-2-agonists and their use as medicaments | BOEHRINGER INGELHEIM INT (DE) | 2007-01-31 | — | — | CN | disclosed |