Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CTSV | O60911 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19327157 | 0.88 | CTSV (0.46) | MEN1KMT2AMAPTCTSVCTSL | |
| SCHEMBL561090 | 0.88 | MAOB (0.56) | MEN1KMT2AMAPTCTSVCTSL | |
| SCHEMBL19327132 | 0.82 | MEN1 (0.45) | MEN1KMT2ACTSVCTSLBACE1 | |
| SCHEMBL28849620 | 0.80 | MAOB (0.49) | MEN1KMT2AMAPTMAOBL3MBTL1 | |
| SCHEMBL19341723 | 0.79 | MAPT (0.45) | MEN1KMT2AMAPTPKML3MBTL1 | |
| SCHEMBL27684770 | 0.78 | BACE1 (0.52) | MEN1KMT2AMAPTBACE1MAOB | |
| SCHEMBL27647870 | 0.78 | MAPT (0.45) | MEN1KMT2AMAPTBACE1MAOB | |
| SCHEMBL27585583 | 0.77 | CTSV (0.54) | MEN1KMT2AMAPTCTSVCTSL | |
| SCHEMBL27852320 | 0.76 | MAOB (0.63) | MEN1KMT2AMAPTMAOBRAB9A | |
| SCHEMBL27519354 | 0.76 | MAPT (0.54) | MEN1KMT2AMAPTMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110215933-A | A kind of preparation method of respiratory medicine object Ao Dateluo intermediate | 马海红 | 2019-09-10 | — | — | CN | claimed |
| CN-110215933-A | A kind of preparation method of respiratory medicine object Ao Dateluo intermediate | 马海红 | 2019-09-10 | — | — | CN | disclosed |
| CN-107108502-A | having beta2Biphenyl derivatives with receptor agonism and M receptor antagonistic activity and application thereof in medicine | 四川海思科制药有限公司 | 2017-08-29 | — | — | CN | disclosed |