Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 5/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750554 | 0.86 | TSHR (0.43) | ECE1ALDH1A1 | |
| SCHEMBL27583416 | 0.83 | ALDH1A1 (0.39) | ECE1ALDH1A1MTNR1BMTNR1A | |
| SCHEMBL14453237 | 0.80 | HTT (0.40) | ECE1ALDH1A1HTTMTNR1BMTNR1A | |
| SCHEMBL14453238 | 0.77 | IDO1 (0.43) | — | |
| SCHEMBL31757931 | 0.77 | IDO1 (0.43) | — | |
| SCHEMBL31757939 | 0.77 | IDO1 (0.43) | — | |
| SCHEMBL30481743 | 0.75 | IDO1 (0.42) | ECE1TRPM8CA1CA2HTT | |
| SCHEMBL31609333 | 0.75 | IDO1 (0.42) | ECE1TRPM8CA1CA2HTT | |
| SCHEMBL255287 | 0.75 | IDO1 (0.42) | ECE1TRPM8CA1CA2HTT | |
| SCHEMBL5965470 | 0.75 | IDO1 (0.42) | ECE1TRPM8CA1CA2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1798559-B | Quinoline-2-one-derivatives for the treatment of airways diseases | NOVARTIS AG | 2010-05-12 | — | — | CN | disclosed |
| CN-1798559-A | Quinoline-2-one-derivatives for the treatment of airways diseases | NOVARTIS AG (CH) | 2006-07-05 | — | — | CN | disclosed |